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Orphan Annie-eye Nuclei

The nucleus forms the central part of a cell which controls gene expression and mediates the replication of deoxyribonucleic acid (DNA) during cell cycle. Two main types of nuclei which we usually encounter are the open face (transcriptionally active cells), consisting of large areas of euchromatin and the closed faced nucleus (transcriptionally inactive cells-most of its genome is in inactive ...

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stimuli: A meta-analysis. Pain 1998; 74:181–7 33. Carvalho B, Angst MS, Fuller AJ, Lin E, Mathusamy AD, Riley ET: Experimental heat pain for detecting pregnancy-induced analgesia in humans. Anesth Analg 2006; 103:1283–7 34. Gintzler AR: Endorphin-mediated increases in pain threshold during pregnancy. Science 1980; 210:193–5 35. Sander HW, Gintzler AR: Spinal cord mediation of the opioid analges...

ANNIE: integrated de novo protein sequence annotation

Function prediction of proteins with computational sequence analysis requires the use of dozens of prediction tools with a bewildering range of input and output formats. Each of these tools focuses on a narrow aspect and researchers are having difficulty obtaining an integrated picture. ANNIE is the result of years of close interaction between computational biologists and computer scientists an...